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Repligen Corporation


Repligen Corporation是蛋白A的領先制造商,蛋白A是用于制造基于單克隆抗體的治療劑的關鍵試劑。我們還提供幾種生長因子產品,用于提高生物制造中的細胞培養生產力。在生物制造技術蓬勃發展的領域,我們開發并銷售了一系列用于生物制品純化過程的OPUS?一次性色譜柱.專注領域生命科學、生物制造、生物過程開發、色譜、蛋白A、生長因子、預填充柱。


Repligen is a bioprocessing-focused life sciences company bringing over 30 years of  expertise and innovation to our customers. We are inspiring advances in bioprocessing through the development and commercialization of high-value products and flexible solutions that address critical steps in the production of biologic drugs, principally monoclonal antibodies.


Our core Protein A affinity ligands business is complemented by an expanding suite of technology-leading bioprocessing products that we sell direct to biopharmaceutical companies and contract manufacturers worldwide. All of our bioprocessing products are meaningfully differentiated from alternatives to the benefit of our customers. Our Protein A ligands are used to purify over 50 monoclonal antibody-based drugs on the market and more than 300 in clinical development.  Our XCell? ATF cell concentration device, and cell culture supplements are at the forefront of innovation in bioprocessing.  To provide customers with the broadest selection of pre-packed chromatography columns from bench-scale to production-scale, Repligen acquired Atoll GmBH of Weingarten, Germany, solidifying Repligen as a leading supplier in this fast-growing segment.


產品列表:


XCell? ATF System - Stainless Steel

XCell? ATF Cell Retention System

The XCell? ATF System in stainless steel comes in five different sizes for operation from lab-scale to production-scale. Each system consists of a diaphragm pump in a stainless steel housing, a single-use hollow fiber filter cartridge, and a control system.

?XCell? ATF 2 System

?XCell? ATF 4 System

?XCell? ATF 6 System

?XCell? ATF 8 System

?XCell? ATF 10 System

 XCell? ATF System - Stainless Steel

Technology

The XCell? ATF System is based on award-winning Alternating Tangential Flow (XCell? ATF) technology, created by the action of a diaphragm moving upward and downward within a pump head, connected to a filter housing and attached to a bioreactor. Alternating tangential flow is attained by the action of a diaphragm pump.

XCell? atf technology

Benefits

ATF Cell Retention System

?Continuous, provides clarified harvest ready for capture chromatography

?Efficient, delivers 100% cell retention, increases productivity

?Intensified, generates high cell concentration and viability

?Flexible, connects to any bioreactor and can be used in a variety of applications

?Gentle, reduces cell stress, increases cell viability and productivity

?Easy to use, reduces setup time and user training

?Scalable, adapts from development-scale to production-scale

?Self-cleaning, reduces biofilm build up on the hollow fiber filter

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